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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 4
Species	Homo sapiens (Human)
Gene	P2RY4
Synonym	UNR pyrimidinoceptor pyrimidinergic receptor P2Y P2Y4R P2Y4 receptor P2Y4 P2Y purinoceptor 4 P2Y ATP receptor 4 P2P NRU uridine nucleotide receptor [ Show all ]
Disease	N/A
Length	365
Amino acid sequence	MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL
UniProt	P51582
Protein Data Bank	N/A
GPCR-HGmod model	P51582
3D structure model	This predicted structure model is from GPCR-EXP P51582.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2123
IUPHAR	325
DrugBank	N/A

Ligand

Name	CHEMBL496030
Molecular formula	C20H13N2O6S-
IUPAC name	1-amino-4-(4-hydroxyanilino)-9,10-dioxoanthracene-2-sulfonate
Molecular weight	409.392
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	3.1
Synonyms	BDBM50268725 sodium 1-amino-4-(4-hydroxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
Inchi Key	KFBGXLCLNATBFL-UHFFFAOYSA-M
Inchi ID	InChI=1S/C20H14N2O6S/c21-18-15(29(26,27)28)9-14(22-10-5-7-11(23)8-6-10)16-17(18)20(25)13-4-2-1-3-12(13)19(16)24/h1-9,22-23H,21H2,(H,26,27,28)/p-1
PubChem CID	59448191
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50268725
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2220.0 nM	PMID21207957	BindingDB
IC50	2370.0 nM	PMID20146483	BindingDB

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