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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Alpha-1A adrenergic receptor
Species	Rattus norvegicus (Rat)
Gene	Adra1a
Synonym	alpha1c alpha1A-adrenoceptor alpha1a Alpha-1C adrenergic receptor Alpha-1A adrenoreceptor Alpha-1A adrenoceptor alpha-1A adrenergic receptor ADRA1C alpha 1C-adrenergic receptor alpha 1A-adrenoreceptor alpha 1A-adrenoceptor adrenergic receptor, alpha 1a adrenergic receptor alpha 1c adrenergic alpha 1c receptor ADRA1L1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	466
Amino acid sequence	MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
UniProt	P43140
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL319
IUPHAR	22
DrugBank	N/A

Ligand

Name	INDORAMIN
Molecular formula	C22H25N3O
IUPAC name	N-[1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl]benzamide
Molecular weight	347.462
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	4.1
Synonyms	Benzamide, N-(1-(2-(1H-indol-3-yl)ethyl)-4-piperidinyl)- GTPL501 Indoramina KS-00002WRM N-(1-(2-Indol-3-ylethyl)-4-piperidyl)benzamide Oprea1_130443 SMR000567879 AC1L1PYQ Benzamide, N-[1-[2-(1H-indol-3-yl)ethyl]-4-piperidinyl]- D04531 IDI1_016359 Indoramine [INN-French] Maybridge3_004972 N-[1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl]benzamide PDSP2_001083 WY 21901 3-(2-(4-Benzamidopiperid-1-yl)ethyl)indole AF-0013 Baratol CCG-41146 DTXSID7048370 Indoramin [USAN:BAN:INN] Indoraminum [INN-Latin] MolPort-002-914-870 N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide(Indoramin) SCHEMBL49517 Benzamide, N-(1-(2-indol-3-ylethyl)-4-piperidyl)- CHEMBL279516 HMS1445B22 Indoramina [INN-Spanish] L001292 N-(1-[2-(1H-Indol-3-yl)ethyl]-4-piperidinyl)benzamide # PDSP1_001099 SR-01000631243-1 0Z802HMY7H AC1Q5FDP BRN 0494035 INDORAMINN-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide MCULE-9172964530 N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide PDSP2_001407 Wy-21901 3-[2-(4-Benzamido-1-piperidyl)ethyl]indole AJ-08048 BDBM50033113 CHEBI:135470 EINECS 248-041-5 Indoramin [USAN:INN:BAN] JXZZEXZZKAWDSP-UHFFFAOYSA-N N-(1-(2-(1H-Indol-3-yl)ethyl)-4-piperidinyl)benzamide NCGC00165810-01 SCHEMBL49518 Benzamide, N-[1-(2-indol-3-ylethyl)-4-piperidyl]- D02LHR HMS2851P23 Indoramine LS-27034 N-[1-(2-Indol-3-ylethyl)-4-piperidyl]benzamide PDSP1_001423 UNII-0Z802HMY7H 26844-12-2 ACM26844122 AKOS015994528 C22H25N3O DB08950 Indoramin (USAN/INN) Indoraminum MLS001182179 N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide (Indoramin) S052 ZINC1567 3-[2-(4-Benzamidopiperidino)ethyl]indole [ Show all ]
Inchi Key	JXZZEXZZKAWDSP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25N3O/c26-22(17-6-2-1-3-7-17)24-19-11-14-25(15-12-19)13-10-18-16-23-21-9-5-4-8-20(18)21/h1-9,16,19,23H,10-15H2,(H,24,26)
PubChem CID	33625
ChEMBL	CHEMBL279516
IUPHAR	501
BindingDB	50033113
DrugBank	DB08950
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	5.9 nM	PMID17827	BindingDB
Ki	611.0 nM	PMID1706716	BindingDB
Ki	6500.0 nM	PMID17827	BindingDB

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