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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 4
Species	Homo sapiens (Human)
Gene	P2RY4
Synonym	UNR pyrimidinoceptor pyrimidinergic receptor P2Y P2Y4R P2Y4 receptor P2Y4 P2Y purinoceptor 4 P2Y ATP receptor 4 P2P NRU uridine nucleotide receptor [ Show all ]
Disease	N/A
Length	365
Amino acid sequence	MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL
UniProt	P51582
Protein Data Bank	N/A
GPCR-HGmod model	P51582
3D structure model	This predicted structure model is from GPCR-EXP P51582.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2123
IUPHAR	325
DrugBank	N/A

Ligand

Name	CHEMBL391317
Molecular formula	C13H15F3NO13P3S
IUPAC name	[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Molecular weight	575.233
Hydrogen bond acceptor	18
Hydrogen bond donor	6
XlogP	-2.4
Synonyms	BDBM50197696 SCHEMBL6395428 ({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
Inchi Key	JWOOVSDBHPDOSN-QCNRFFRDSA-N
Inchi ID	InChI=1S/C13H15F3NO13P3S/c14-13(15,16)5-1-2-8-6(3-5)17-12(34-8)11-10(19)9(18)7(28-11)4-27-32(23,24)30-33(25,26)29-31(20,21)22/h1-3,7,9-11,18-19H,4H2,(H,23,24)(H,25,26)(H2,20,21,22)/t7-,9-,10-,11-/m1/s1
PubChem CID	10168108
ChEMBL	CHEMBL391317
IUPHAR	N/A
BindingDB	50197696
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<20000.0 nM	PMID17079144	BindingDB,ChEMBL

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