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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Alpha-2A adrenergic receptor
Species	Bos taurus (Bovine)
Gene	ADRA2A
Synonym	Alpha-2A adrenoceptor Alpha-2A adrenoreceptor Alpha-2AAR Alpha-2D adrenergic receptor
Disease	N/A for non-human GPCRs
Length	452
Amino acid sequence	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKKRGRSGQPSAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDATAAELPGSAERRPNGLGPERGGVGPVGAEVESLQVQLNGAPGEPAPAGAGADALDLEESSSSEHAERPPGSRRSERGPRAKGKARASQVKPGDSLPRRGPGATGLGAPTAGPAEERSGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAIGCPVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
UniProt	Q28838
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4744
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL348538
Molecular formula	C12H16N2
IUPAC name	6,8,9,10,11,11a-hexahydro-5H-pyrido[1,2-h][1,7]naphthyridine
Molecular weight	188.274
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	1.6
Synonyms	112114-03-1 5,6,7,8,9,10-Hexahydro-4bH-4,8a-diaza-phenanthrene BDBM50018735 5,8,9,10,11,11a-hexahydro-6H-pyrido[1,2-h]-1,7-naphthyridine
Inchi Key	JWBLYAGFFUSJCB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H16N2/c1-2-8-14-9-6-10-4-3-7-13-12(10)11(14)5-1/h3-4,7,11H,1-2,5-6,8-9H2
PubChem CID	14004032
ChEMBL	CHEMBL348538
IUPHAR	N/A
BindingDB	50018735
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1995.0 nM	PMID2831365	BindingDB
Ki	1995.26 nM	PMID2831365	ChEMBL
Ki	2000.0 nM	PMID2831365	BindingDB,ChEMBL

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