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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP2 subtype
Species	Mus musculus (Mouse)
Gene	Ptger2
Synonym	EP2 receptor PGE receptor EP2 subtype PGE2 receptor EP2 subtype prostaglandin E receptor 2 (subtype EP2), 53kDa prostanoid EP2 receptor Ptger-ep2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	362
Amino acid sequence	MDNFLNDSKLMEDCKSRQWLLSGESPAISSVMFSAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESHACTYFAFTMTFFSLATMLMLFAMALERYLSIGYPYFYRRHLSRRGGLAVLPVIYGASLLFCSLPLLNYGEYVQYCPGTWCFIRHGRTAYLQLYATMLLLLIVAVLACNISVILNLIRMHRRSRRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAICSLPFTIFAYMDETSSLKEKWDLRALRFLSVNSIIDPWVFAILRPPVLRLMRSVLCCRTSLRTQEAQQTSCSTQSSASKQTDLCGQL
UniProt	Q62053
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2488
IUPHAR	341
DrugBank	N/A

Ligand

Name	CHEMBL603633
Molecular formula	C24H22N2O4
IUPAC name	2-[2-(2-naphthalen-2-ylethoxy)-4-(pyrazol-1-ylmethyl)phenoxy]acetic acid
Molecular weight	402.45
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.6
Synonyms	SCHEMBL2970375 BDBM35863 phenoxyacetic acid analogue, 19
Inchi Key	JUZWEMPFFFBUCL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H22N2O4/c27-24(28)17-30-22-9-7-19(16-26-12-3-11-25-26)15-23(22)29-13-10-18-6-8-20-4-1-2-5-21(20)14-18/h1-9,11-12,14-15H,10,13,16-17H2,(H,27,28)
PubChem CID	10272453
ChEMBL	CHEMBL603633
IUPHAR	N/A
BindingDB	35863
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID19700331	BindingDB,ChEMBL

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