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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Substance-K receptor
Species	Oryctolagus cuniculus (Rabbit)
Gene	TACR2
Synonym	Neurokinin A receptor NK-2 receptor NK-2R SKR Tachykinin receptor 2
Disease	N/A for non-human GPCRs
Length	384
Amino acid sequence	MGACDIVTEANISSDIDSNATGVTAFSMPGWQLALWATAYLALVLVAVVGNATVIWIILAHRRMRTVTNYFIVNLALADLCMATFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSGPGTKAVIAGIWLVALALAFPQCFYSTITMDQGATKCVVAWPEDSGGKMLLLYHLTVIALIYFLPLVVMFVAYSVIGFKLWRRTVPGHQTHGANLRHLRAKKKFVKTMVLVVVTFAVCWLPYHLYFLLGHFQDDIYCRKFIQQVYLVLFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDKLELTHTPSLSVRVNRCHTKETLFLVGDVAPSEAANGQAGGPQDGGAYDF
UniProt	P79218
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3433
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL2373191
Molecular formula	C34H40Cl2N4O3
IUPAC name	1-[(3S)-3-(3,4-dichlorophenyl)-4-[methyl(naphthalene-1-carbonyl)amino]butyl]-N-methyl-4-(2-oxopiperidin-1-yl)piperidine-4-carboxamide
Molecular weight	623.619
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.6
Synonyms	N-Methyl-N-[(2S)-2-(3,4-dichlorophenyl)-4-[4-(methylcarbamoyl)-4-(2-oxopiperidino)piperidino]butyl]naphthalene-1-carboxamide
Inchi Key	JOQPSSZWMNCVRG-AREMUKBSSA-N
Inchi ID	InChI=1S/C34H40Cl2N4O3/c1-37-33(43)34(40-18-6-5-12-31(40)41)16-20-39(21-17-34)19-15-26(25-13-14-29(35)30(36)22-25)23-38(2)32(42)28-11-7-9-24-8-3-4-10-27(24)28/h3-4,7-11,13-14,22,26H,5-6,12,15-21,23H2,1-2H3,(H,37,43)/t26-/m1/s1
PubChem CID	73347244
ChEMBL	CHEMBL2373191
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
pKB	8.44 -	PMID11591520	ChEMBL

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