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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 7b
Species	Rattus norvegicus (Rat)
Gene	Taar7b
Synonym	TaR-12 TaR-7b Trace amine receptor 12 Trace amine receptor 7b
Disease	N/A for non-human GPCRs
Length	358
Amino acid sequence	MATDDDRFPWDQDSILSRDLLSASSMQLCYEKLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTASVSGKCITFSWLLSIIYSFSLFYTGVNEAGLEDLVSALTCVGGCQIAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
UniProt	Q923X8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2176813
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3641703
Molecular formula	C15H18F2N4O
IUPAC name	1-(2,2-difluoroethyl)-N-(4-morpholin-2-ylphenyl)pyrazol-3-amine
Molecular weight	308.333
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	1.9
Synonyms	SCHEMBL12609881 US8802673, 150 BDBM129508
Inchi Key	JOQMWJQZABZALY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H18F2N4O/c16-14(17)10-21-7-5-15(20-21)19-12-3-1-11(2-4-12)13-9-18-6-8-22-13/h1-5,7,13-14,18H,6,8-10H2,(H,19,20)
PubChem CID	68325626
ChEMBL	CHEMBL3641703
IUPHAR	N/A
BindingDB	129508
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	148.6 nM	, None	BindingDB,ChEMBL

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