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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 7b
Species	Rattus norvegicus (Rat)
Gene	Taar7b
Synonym	TaR-12 TaR-7b Trace amine receptor 12 Trace amine receptor 7b
Disease	N/A for non-human GPCRs
Length	358
Amino acid sequence	MATDDDRFPWDQDSILSRDLLSASSMQLCYEKLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTASVSGKCITFSWLLSIIYSFSLFYTGVNEAGLEDLVSALTCVGGCQIAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
UniProt	Q923X8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2176813
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3701934
Molecular formula	C17H18ClFN2O
IUPAC name	N-[(4-chloro-2-fluorophenyl)methyl]-4-[(2S)-morpholin-2-yl]aniline
Molecular weight	320.792
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.2
Synonyms	SCHEMBL12609552 US8802673, 35 BDBM129393
Inchi Key	JEKYPWQCOHEEPX-QGZVFWFLSA-N
Inchi ID	InChI=1S/C17H18ClFN2O/c18-14-4-1-13(16(19)9-14)10-21-15-5-2-12(3-6-15)17-11-20-7-8-22-17/h1-6,9,17,20-21H,7-8,10-11H2/t17-/m1/s1
PubChem CID	68325395
ChEMBL	CHEMBL3701934
IUPHAR	N/A
BindingDB	129393
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	188.3 nM	, None	BindingDB,ChEMBL

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