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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Cavia porcellus (Guinea pig)
Gene	ADORA1
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD
UniProt	P47745
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2304404
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	1-Propylxanthine
Molecular formula	C8H10N4O2
IUPAC name	1-propyl-3,7-dihydropurine-2,6-dione
Molecular weight	194.194
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	0.6
Synonyms	1-propyl-3,7-dihydropurine-2,6-dione BDBM50001490 SCHEMBL8930198 1H-Purine-2,6-dione, 3,7-dihydro-1-propyl- CTK4A2909 AC1L2TY0 IWBONKMODGBEOX-UHFFFAOYSA-N 1H-Purine-2,6-dione,3,9-dihydro-1-propyl- D0LD0X 1-Propyl-3,7-dihydro-purine-2,6-dione ACMC-1BNN6 SCHEMBL4423680 104285-82-7 CHEMBL39986 DTXSID10146367 [ Show all ]
Inchi Key	IWBONKMODGBEOX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C8H10N4O2/c1-2-3-12-7(13)5-6(10-4-9-5)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,14)
PubChem CID	128525
ChEMBL	CHEMBL39986
IUPHAR	N/A
BindingDB	50001490
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC15	<100.0 uM	PMID1331453	ChEMBL
Ki	3300.0 nM	PMID1331453	BindingDB,ChEMBL

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