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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-Propylxanthine
Molecular formula	C8H10N4O2
IUPAC name	1-propyl-3,7-dihydropurine-2,6-dione
Molecular weight	194.194
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	0.6
Synonyms	D0LD0X 1H-Purine-2,6-dione,3,9-dihydro-1-propyl- SCHEMBL4423680 1-Propyl-3,7-dihydro-purine-2,6-dione ACMC-1BNN6 104285-82-7 CHEMBL39986 DTXSID10146367 SCHEMBL8930198 1-propyl-3,7-dihydropurine-2,6-dione BDBM50001490 1H-Purine-2,6-dione, 3,7-dihydro-1-propyl- CTK4A2909 IWBONKMODGBEOX-UHFFFAOYSA-N AC1L2TY0 [ Show all ]
Inchi Key	IWBONKMODGBEOX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C8H10N4O2/c1-2-3-12-7(13)5-6(10-4-9-5)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,14)
PubChem CID	128525
ChEMBL	CHEMBL39986
IUPHAR	N/A
BindingDB	50001490
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
143178	Adenosine receptor A1	P47745	ADORA1	Cavia porcellus (Guinea pig)	326
143179	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
143180	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
143182	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
143184	Adenosine receptor A2a	P46616	ADORA2A	Cavia porcellus (Guinea pig)	409
143181	Adenosine receptor A2b	P29276	Adora2b	Rattus norvegicus (Rat)	332
143183	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
143185	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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