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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Rattus norvegicus (Rat)
Gene	Adrb2
Synonym	beta2-adrenoceptor Beta-2 adrenoreceptor Beta-2 adrenoceptor beta-2 adrenergic receptor beta 2-AR B2AR adrenoceptor beta 2, surface adrenergic receptor ADRBR ADRB2R Adrb-2 Gpcr7 [ Show all ]
Disease	N/A for non-human GPCRs
Length	418
Amino acid sequence	MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQAIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRANLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
UniProt	P10608
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3754
IUPHAR	29
DrugBank	N/A

Ligand

Name	CHEMBL206100
Molecular formula	C4H5N3O4
IUPAC name	4-(hydroxymethyl)-2-oxido-1,2,5-oxadiazol-2-ium-3-carboxamide
Molecular weight	159.101
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	-0.9
Synonyms	CAS-1609 4-hydroxymethyl-2-oxy-furazan-3-carboxylic acid amide CTK8H1175 AKOS023557327 ZINC1484690 158590-73-9 4-hydroxymethyl-3-furoxancarboxamide KB-71654 BDBM50186613 4-(hydroxymethyl)-1,2,5-Oxadiazole-3-carboxamide 2-oxide SCHEMBL429693 [ Show all ]
Inchi Key	IPHRXVUYWVWSTP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C4H5N3O4/c5-4(9)3-2(1-8)6-11-7(3)10/h8H,1H2,(H2,5,9)
PubChem CID	10103414
ChEMBL	CHEMBL206100
IUPHAR	N/A
BindingDB	50186613
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	>50.0 %	PMID17845020	ChEMBL
EC50	6300.0 nM	PMID17845020	BindingDB,ChEMBL

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