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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Substance-P receptor
Species	Cavia porcellus (Guinea pig)
Gene	TACR1
Synonym	NK-1 receptor NK-1R SPR Tachykinin receptor 1
Disease	N/A for non-human GPCRs
Length	407
Amino acid sequence	MDNVLPVDSDLFPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPGRVVCMIEWPSHPDKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAADYEGLEMKSTRYFQTQGSVYKVSRLETTISTVVGAHEEDPEEGPKATPSSLDLTSNGSSRSNSKTVTESSSFYSNMLS
UniProt	P30547
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3942
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL291868
Molecular formula	C31H31N3O4S
IUPAC name	(4R)-1-(1-benzothiophene-2-carbonyl)-N-[(2R)-1-[benzyl(methyl)amino]-1-oxo-3-phenylpropan-2-yl]-4-hydroxypyrrolidine-2-carboxamide
Molecular weight	541.666
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.6
Synonyms	(R)-1-(Benzo[b]thiophene-2-carbonyl)-4-hydroxy-pyrrolidine-2-carboxylic acid [(R)-1-(benzyl-methyl-carbamoyl)-2-phenyl-ethyl]-amide BDBM50030198
Inchi Key	ASZUNVYZNVUWFW-YFHSQZFMSA-N
Inchi ID	InChI=1S/C31H31N3O4S/c1-33(19-22-12-6-3-7-13-22)30(37)25(16-21-10-4-2-5-11-21)32-29(36)26-18-24(35)20-34(26)31(38)28-17-23-14-8-9-15-27(23)39-28/h2-15,17,24-26,35H,16,18-20H2,1H3,(H,32,36)/t24-,25-,26?/m1/s1
PubChem CID	44305927
ChEMBL	CHEMBL291868
IUPHAR	N/A
BindingDB	50030198
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	19.9 nM	PMID7518002	ChEMBL
IC50	20.0 nM	PMID7518002	BindingDB

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