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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 5
Species	Homo sapiens (Human)
Gene	LPAR5
Synonym	G-protein coupled receptor 92 LPAR5 LPA5 receptor LPA-5 LPA receptor 5 G protein-coupled receptor 92 GPR92 G-protein coupled receptor 93 GPR93 [ Show all ]
Disease	N/A
Length	372
Amino acid sequence	MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
UniProt	Q9H1C0
Protein Data Bank	N/A
GPCR-HGmod model	Q9H1C0
3D structure model	This predicted structure model is from GPCR-EXP Q9H1C0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5700
IUPHAR	124
DrugBank	N/A

Ligand

Name	AC1LRAEE
Molecular formula	C20H13N3O5
IUPAC name	5-(3-nitrophenoxy)-2-(pyridin-3-ylmethyl)isoindole-1,3-dione
Molecular weight	375.34
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.7
Synonyms	5-(3-nitrophenoxy)-2-(pyridin-3-ylmethyl)isoindole-1,3-dione MolPort-001-620-641 AKOS003243340 ZINC1209665 CHEMBL595395 AB00096027-01 Oprea1_387399 Cambridge id 5759401 5-(3-nitrophenoxy)-2-(pyridin-3-ylmethyl)-1H-isoindole-1,3(2H)-dione MCULE-5764327349 STK032260 [ Show all ]
Inchi Key	IGPKNBILKWYGSI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H13N3O5/c24-19-17-7-6-16(28-15-5-1-4-14(9-15)23(26)27)10-18(17)20(25)22(19)12-13-3-2-8-21-11-13/h1-11H,12H2
PubChem CID	1365291
ChEMBL	CHEMBL595395
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	38.0 %	PMID19800804	ChEMBL

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