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GPCR

NameBeta-2 adrenergic receptor
SpeciesRattus norvegicus (Rat)
GeneAdrb2
Synonymbeta2-adrenoceptor
Beta-2 adrenoreceptor
Beta-2 adrenoceptor
beta-2 adrenergic receptor
beta 2-AR
[ Show all ]
DiseaseN/A for non-human GPCRs
Length418
Amino acid sequenceMEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQAIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRANLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
UniProtP10608
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3754
IUPHAR29
DrugBankN/A

Ligand

NameCHEMBL3230442
Molecular formulaC27H38N2O9
IUPAC nameN-[4-[3-[2-(3,4-dimethoxyphenyl)ethylamino]-2-hydroxypropoxy]phenyl]hexanamide;oxalic acid
Molecular weight534.606
Hydrogen bond acceptor10
Hydrogen bond donor5
XlogPNone
SynonymsN/A
Inchi KeyASEOCMJZPNWOAL-UHFFFAOYSA-N
Inchi IDInChI=1S/C25H36N2O5.C2H2O4/c1-4-5-6-7-25(29)27-20-9-11-22(12-10-20)32-18-21(28)17-26-15-14-19-8-13-23(30-2)24(16-19)31-3;3-1(4)2(5)6/h8-13,16,21,26,28H,4-7,14-15,17-18H2,1-3H3,(H,27,29);(H,3,4)(H,5,6)
PubChem CID12541326
ChEMBLCHEMBL3230442
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
Partition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
Kapp27.0 uMPMID37339ChEMBL

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