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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Muscarinic acetylcholine receptor M2
Species	Sus scrofa (Pig)
Gene	CHRM2
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	466
Amino acid sequence	MNNSTNSSNSGLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQEPVSPSLVQGRIVKPNNNNMPGSDEALEHNKIQNGKAPRDAVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIKIVTKTQKSDSCTPANTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
UniProt	P06199
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4781
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL33656
Molecular formula	C23H24Cl2N4O2+2
IUPAC name	(E)-1-[1-[3-[4-[(E)-(2,6-dichlorophenyl)methoxyiminomethyl]pyridin-1-ium-1-yl]propyl]pyridin-1-ium-4-yl]-N-methoxymethanimine
Molecular weight	459.371
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.8
Synonyms	BDBM50041518 4-((E)-{[(2,6-dichlorobenzyl)oxy]imino}methyl)-1-propyl-3yl-(4-(Methoxyimino-methyl)-pyridinium)pyridinium
Inchi Key	IBRSSKUPVHTLLN-CTVDDJEBSA-N
Inchi ID	InChI=1S/C23H24Cl2N4O2/c1-30-26-16-19-6-12-28(13-7-19)10-3-11-29-14-8-20(9-15-29)17-27-31-18-21-22(24)4-2-5-23(21)25/h2,4-9,12-17H,3,10-11,18H2,1H3/q+2/b26-16+,27-17+
PubChem CID	10077592
ChEMBL	CHEMBL33656
IUPHAR	N/A
BindingDB	50041518
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	4500.0 nM	PMID8182702	BindingDB,ChEMBL
nH	1.2 -	PMID8182702	ChEMBL

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