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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 2
Species	Rattus norvegicus (Rat)
Gene	Sstr2
Synonym	somatotropin release-inhibiting factor receptor SRIF-1 SS-2-R SS2-R SS2R SST2 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	369
Amino acid sequence	MELTSEQFNGSQVWIPSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGAEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
UniProt	P30680
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2978
IUPHAR	356
DrugBank	N/A

Ligand

Name	CHEMBL250314
Molecular formula	C26H31F3N4O5S
IUPAC name	[2-[4-[(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline-3-carbonyl]piperazin-1-yl]pyridin-3-yl] trifluoromethanesulfonate
Molecular weight	568.612
Hydrogen bond acceptor	11
Hydrogen bond donor	0
XlogP	3.8
Synonyms	BDBM50423328
Inchi Key	HXSFAPIPSVCGNS-SFHLNBCPSA-N
Inchi ID	InChI=1S/C26H31F3N4O5S/c1-31-16-19(13-18-14-20-17(15-21(18)31)5-3-6-22(20)37-2)25(34)33-11-9-32(10-12-33)24-23(7-4-8-30-24)38-39(35,36)26(27,28)29/h3-8,18-19,21H,9-16H2,1-2H3/t18-,19-,21-/m1/s1
PubChem CID	44441872
ChEMBL	CHEMBL250314
IUPHAR	N/A
BindingDB	50423328
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Kd	10471.0 nM	PMID17512199	BindingDB
Kd	10471.3 nM	PMID17512199	ChEMBL

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