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Name | Adenosine receptor A3 |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Adora3 |
Synonym | A3 receptor A3AR Adenosine receptor A3 ARA3 TGPCR1 |
Disease | N/A for non-human GPCRs |
Length | 320 |
Amino acid sequence | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE |
UniProt | P28647 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3360 |
IUPHAR | 21 |
DrugBank | N/A |
Name | CHEMBL2113492 |
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Molecular formula | C15H22N6O4 |
IUPAC name | (2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-N-pentyloxolane-2-carboxamide |
Molecular weight | 350.379 |
Hydrogen bond acceptor | 8 |
Hydrogen bond donor | 4 |
XlogP | 0.7 |
Synonyms | 5'-Oxo-5'-(pentylamino)-5'-deoxyadenosine BDBM50409304 |
Inchi Key | HPUURONQWKICJL-BQVMBELUSA-N |
Inchi ID | InChI=1S/C15H22N6O4/c1-2-3-4-5-17-14(24)11-9(22)10(23)15(25-11)21-7-20-8-12(16)18-6-19-13(8)21/h6-7,9-11,15,22-23H,2-5H2,1H3,(H,17,24)(H2,16,18,19)/t9-,10+,11-,15+/m0/s1 |
PubChem CID | 10089226 |
ChEMBL | CHEMBL2113492 |
IUPHAR | N/A |
BindingDB | 50409304 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 5560.0 nM | PMID11170630 | ChEMBL |
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