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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 2
Species	Rattus norvegicus (Rat)
Gene	Sstr2
Synonym	somatotropin release-inhibiting factor receptor SRIF-1 SS-2-R SS2-R SS2R SST2 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	369
Amino acid sequence	MELTSEQFNGSQVWIPSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGAEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
UniProt	P30680
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2978
IUPHAR	356
DrugBank	N/A

Ligand

Name	CHEMBL254505
Molecular formula	C27H32BrN5O2
IUPAC name	6-[4-[(6aR,9R,10aR)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-ethylpyridin-2-one
Molecular weight	538.49
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.5
Synonyms	BDBM50423480
Inchi Key	HINUKPGHYMZLRL-SFGWALBWSA-N
Inchi ID	InChI=1S/C27H32BrN5O2/c1-3-33-23(8-5-9-24(33)34)31-10-12-32(13-11-31)27(35)17-14-19-18-6-4-7-21-25(18)20(26(28)29-21)15-22(19)30(2)16-17/h4-9,17,19,22,29H,3,10-16H2,1-2H3/t17-,19-,22-/m1/s1
PubChem CID	44447049
ChEMBL	CHEMBL254505
IUPHAR	N/A
BindingDB	50423480
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Kd	26302.7 nM	PMID18162395	ChEMBL
Kd	26303.0 nM	PMID18162395	BindingDB

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