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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1 angiotensin II receptor
Species	Oryctolagus cuniculus (Rabbit)
Gene	AGTR1
Synonym	Angiotensin II type-1 receptor AT1
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
UniProt	P34976
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3948
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL166428
Molecular formula	C33H37N3O6S
IUPAC name	6-oxo-6-[[2-[4-[(4-oxo-6-propan-2-yl-2-propylquinazolin-3-yl)methyl]phenyl]phenyl]sulfonylamino]hexanoic acid
Molecular weight	603.734
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.8
Synonyms	6-[4''-(6-Isopropyl-4-oxo-2-propyl-4H-quinazolin-3-ylmethyl)-biphenyl-2-sulfonylamino]-6-oxo-hexanoic acid BDBM50282446
Inchi Key	ABSJDIWFRVISBD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H37N3O6S/c1-4-9-30-34-28-19-18-25(22(2)3)20-27(28)33(40)36(30)21-23-14-16-24(17-15-23)26-10-5-6-11-29(26)43(41,42)35-31(37)12-7-8-13-32(38)39/h5-6,10-11,14-20,22H,4,7-9,12-13,21H2,1-3H3,(H,35,37)(H,38,39)
PubChem CID	44379185
ChEMBL	CHEMBL166428
IUPHAR	N/A
BindingDB	50282446
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	25.0 nM	, Bioorg. Med. Chem. Lett., (1994) 4:1:75	BindingDB,ChEMBL

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