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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cannabinoid receptor 1
Species	Rattus norvegicus (Rat)
Gene	Cnr1
Synonym	SKR6R Neuronal cannabinoid receptor Central cannabinoid receptor CB1R CB1 receptor CB1 CB-R Cann7 Cann6 Brain-type cannabinoid receptor THC receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	473
Amino acid sequence	MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
UniProt	P20272
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3571
IUPHAR	56
DrugBank	N/A

Ligand

Name	CHEMBL423602
Molecular formula	C25H43NO
IUPAC name	(5Z,8Z,11Z,14Z)-2,2-dimethyl-N-propan-2-ylicosa-5,8,11,14-tetraenamide
Molecular weight	373.625
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	7.8
Synonyms	(5Z,8Z,11Z,14Z)-2,2-dimethyl-N-propan-2-ylicosa-5,8,11,14-tetraenamide N-isopropyl-2,2-dimethyl-5Z,8Z,11Z,14Z-eicosatetraenoyl amine BDBM50056462 LMFA08020036 N-isopropyl-alpha,alpha-dimethylarachidonoylamide (5Z,8Z,11Z,14Z)-2,2-Dimethyl-icosa-5,8,11,14-tetraenoic acid isopropylamide N-isopropyl alpha,alpha-dimethylarachidonoyl amine AC1NR28V [ Show all ]
Inchi Key	APMHRGDNLGREMG-AILJCPQKSA-N
Inchi ID	InChI=1S/C25H43NO/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-25(4,5)24(27)26-23(2)3/h10-11,13-14,16-17,19-20,23H,6-9,12,15,18,21-22H2,1-5H3,(H,26,27)/b11-10-,14-13-,17-16-,20-19-
PubChem CID	5283419
ChEMBL	CHEMBL423602
IUPHAR	N/A
BindingDB	50056462
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	7.2 nM	PMID9057852	BindingDB,ChEMBL

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