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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 7b
Species	Rattus norvegicus (Rat)
Gene	Taar7b
Synonym	TaR-12 TaR-7b Trace amine receptor 12 Trace amine receptor 7b
Disease	N/A for non-human GPCRs
Length	358
Amino acid sequence	MATDDDRFPWDQDSILSRDLLSASSMQLCYEKLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTASVSGKCITFSWLLSIIYSFSLFYTGVNEAGLEDLVSALTCVGGCQIAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
UniProt	Q923X8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2176813
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3701927
Molecular formula	C17H21N3O2
IUPAC name	N-[(6-methoxypyridin-2-yl)methyl]-4-[(2S)-morpholin-2-yl]aniline
Molecular weight	299.374
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	1.7
Synonyms	BDBM129386 SCHEMBL12609702 US8802673, 28
Inchi Key	HAXZLYPMPDNFIJ-MRXNPFEDSA-N
Inchi ID	InChI=1S/C17H21N3O2/c1-21-17-4-2-3-15(20-17)11-19-14-7-5-13(6-8-14)16-12-18-9-10-22-16/h2-8,16,18-19H,9-12H2,1H3/t16-/m1/s1
PubChem CID	68325487
ChEMBL	CHEMBL3701927
IUPHAR	N/A
BindingDB	129386
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	561.0 nM	, None	BindingDB,ChEMBL

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