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GPCR

NameLysophosphatidic acid receptor 2
SpeciesHomo sapiens (Human)
GeneLPAR2
Synonymendothelial differentiation gene 4, lysophosphatidic acid G-protein-coupled receptor 4
LPA receptor 2
LPA-2
Edg4
Lysophosphatidic acid receptor Edg-4
[ Show all ]
DiseaseN/A
Length351
Amino acid sequenceMVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
UniProtQ9HBW0
Protein Data BankN/A
GPCR-HGmod modelQ9HBW0
3D structure modelThis predicted structure model is from GPCR-EXP Q9HBW0.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3724
IUPHAR273
DrugBankN/A

Ligand

NameCHEMBL200003
Molecular formulaC21H40KO5PS
IUPAC namepotassium;[(2R,4S)-2-[(E)-heptadec-9-enyl]-1,3-dioxolan-4-yl]methoxy-hydroxy-oxido-sulfanylidene-lambda5-phosphane
Molecular weight474.678
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogPNone
SynonymsN/A
Inchi KeyGZNAXGFXPWIGJD-SCACHBFTSA-M
Inchi IDInChI=1S/C21H41O5PS.K/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-24-18-20(26-21)19-25-27(22,23)28;/h8-9,20-21H,2-7,10-19H2,1H3,(H2,22,23,28);/q;+1/p-1/b9-8+;/t20-,21+;/m0./s1
PubChem CID44406679
ChEMBLCHEMBL200003
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessPartition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
EC501540.0 nMPMID16290140ChEMBL
Emax72.0 %PMID16290140ChEMBL

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