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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Beta-1 adrenergic receptor
Species	Rattus norvegicus (Rat)
Gene	Adrb1
Synonym	adrenergic receptor beta1-adrenoceptor Beta-1 adrenoreceptor Beta-1 adrenoceptor beta-1 adrenergic receptor ADRB1R beta 1-AR B1AR Adrenergic receptor beta 1 Adrb-1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	466
Amino acid sequence	MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAGMGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDDDDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
UniProt	P18090
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3252
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL266619
Molecular formula	C13H21NO4
IUPAC name	4-[3-(tert-butylamino)-2-hydroxypropoxy]benzene-1,2-diol
Molecular weight	255.314
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	1.1
Synonyms	DTXSID60339904 4-[3-(tert-butylamino)-2-hydroxypropoxy]benzene-1,2-diol AC1LBLAW 1,2-Benzenediol, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]- 4-(3-tert-Butylamino-2-hydroxypropyloxy)benzene-1,2-diol GWXLUBAMOLHDHG-UHFFFAOYSA-N BDBM50007476 3-(Phenoxy)propylamine, N-t-butyl-.beta.,3,4-trihydroxy- CTK1I5455 4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1,2-benzenediol # 64309-38-2 Phenoxypropylamine, N-t-butyl-.beta.,3,4-trihydroxy- 4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,2-diol [ Show all ]
Inchi Key	GWXLUBAMOLHDHG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H21NO4/c1-13(2,3)14-7-9(15)8-18-10-4-5-11(16)12(17)6-10/h4-6,9,14-17H,7-8H2,1-3H3
PubChem CID	559926
ChEMBL	CHEMBL266619
IUPHAR	N/A
BindingDB	50007476
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	120.0 nM	PMID1672155	BindingDB,ChEMBL

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