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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H1 receptor
Species	Cavia porcellus (Guinea pig)
Gene	HRH1
Synonym	H1R HH1R
Disease	N/A for non-human GPCRs
Length	488
Amino acid sequence	MSFLPGMTPVTLSNFSWALEDRMLEGNSTTTPTRQLMPLVVVLSSVSLVTVALNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMSILYLHRSAWILGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWLLSFLWVIPILGWHHFMAPTSEPREKKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYIRIYKAVRRHCQHRQLINSSLPSFSEMKLKLENAKVDTRRMGKESPWEDPKRCSKDASGVHTPMPSSQHLVDMPCAAVLSEDEGGEVGTRQMPMLAVGDGRCCEALNHMHSQLELSGQSRATHSISARPEEWTVVDGQSFPITDSDTSTEAAPMGGQPRSGSNSGLDYIKFTWRRLRSHSRQYTSGLHLNRERKAAKQLGCIMAAFILCWIPYFVFFMVIAFCKSCSNEPVHMFTIWLGYLNSTLNPLIYPLCNENFRKTFKRILRIPP
UniProt	P31389
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3943
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL17740
Molecular formula	C12H15N3
IUPAC name	N-benzyl-2-(1H-imidazol-5-yl)ethanamine
Molecular weight	201.273
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	1.3
Synonyms	BDBM50419043 SCHEMBL14415974 1H-Imidazole-5-ethanamine, N-(phenylmethyl)- AKOS014319525 N-Benzyl-1H-imidazole-4-(ethanamine) Benzyl-[2-(1H-imidazol-4-yl)-ethyl]-amine SCHEMBL4605920 AKOS022987924 N-benzyl-2-(1H-imidazol-5-yl)ethanamine benzylhistamine ZINC34349451 7728-61-2 GVOCXQUIZNWEMU-UHFFFAOYSA-N [ Show all ]
Inchi Key	GVOCXQUIZNWEMU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H15N3/c1-2-4-11(5-3-1)8-13-7-6-12-9-14-10-15-12/h1-5,9-10,13H,6-8H2,(H,14,15)
PubChem CID	14712103
ChEMBL	CHEMBL17740
IUPHAR	N/A
BindingDB	50419043
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Agonist activity	0.4 -	PMID6128418	ChEMBL

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