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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mu-type opioid receptor
Species	Cavia porcellus (Guinea pig)
Gene	OPRM1
Synonym	M-OR-1 MOR-1
Disease	N/A for non-human GPCRs
Length	98
Amino acid sequence	YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
UniProt	P97266
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4354
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL93131
Molecular formula	C20H23BrN2O2
IUPAC name	(2S)-2-amino-1-(7-bromo-3,4-dihydro-1H-isoquinolin-2-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propan-1-one
Molecular weight	403.32
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.4
Synonyms	BDBM50218554 (2S)-1-(7-Bromo-1,2,3,4-tetrahydroisoquinoline-2-yl)-2-amino-3-(2,6-dimethyl-4-hydroxyphenyl)-1-propanone
Inchi Key	AODUHUQHBSDMHI-IBGZPJMESA-N
Inchi ID	InChI=1S/C20H23BrN2O2/c1-12-7-17(24)8-13(2)18(12)10-19(22)20(25)23-6-5-14-3-4-16(21)9-15(14)11-23/h3-4,7-9,19,24H,5-6,10-11,22H2,1-2H3/t19-/m0/s1
PubChem CID	44325588
ChEMBL	CHEMBL93131
IUPHAR	N/A
BindingDB	50218554
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	18.0 nM	PMID11133082	BindingDB
Ki	18.2 -	PMID11133082	ChEMBL

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