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BioLiP Library
Download all results in tab-seperated text for 19 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1nq0:A (2.4) BS01 4HY ? GO:0003677 ... P10828 12511610 PDBbind: -logKd/Ki=10.32, IC50=0.048nM
    BindingDB: IC50=0.0407nM
    2 1nq1:A (2.9) BS01 4HY ? GO:0003677 ... P10828 12511610 BindingDB: IC50=0.0407nM
    3 1nq2:A (2.4) BS01 4HY ? GO:0003677 ... P10828 12554782 BindingDB: IC50=0.0407nM
    4 1nuo:A (3.1) BS01 4HY ? GO:0003677 ... P10828 12554782 BindingDB: IC50=0.0407nM
    5 2pin:A (2.3) BS01 4HY ? GO:0003677 ... P10828 17823305 BindingDB: IC50=0.0407nM
    6 2pin:B (2.3) BS01 4HY ? GO:0003677 ... P10828 17823305 BindingDB: IC50=0.0407nM
    7 2pit:A (1.76) BS02 4HY ? N/A P10275 17911242 BindingDB: IC50=34800nM
    8 2piu:A (2.12) BS02 4HY ? N/A P10275 17911242 BindingDB: IC50=34800nM
    9 2piu:A (2.12) BS03 4HY ? N/A P10275 17911242 BindingDB: IC50=34800nM
    10 2pkl:A (2.49) BS03 4HY ? N/A P10275 17911242 BindingDB: IC50=34800nM
    11 2qpy:A (2.5) BS03 4HY ? N/A P19091 17911242
    12 3d57:A (2.2) BS01 4HY ? GO:0003677 ... P10828 18798561 BindingDB: IC50=0.0407nM
    13 3d57:B (2.2) BS01 4HY ? GO:0003677 ... P10828 18798561 BindingDB: IC50=0.0407nM
    14 3jzb:A (2.007) BS01 4HY ? GO:0003677 ... P10827 19926848 MOAD: ic50~0.1nM
    PDBbind: -logKd/Ki=9.01, IC50=0.97nM
    BindingDB: IC50=0.14nM
    15 3jzc:A (2.5) BS01 4HY ? GO:0003677 ... P10828 19926848 MOAD: ic50~1nM
    PDBbind: -logKd/Ki=8.53, IC50=2.94nM
    BindingDB: IC50=0.0407nM
    16 4yx9:A (1.75) BS01 4HY ? GO:0016787 ... A0A0M3KL26 26136396 MOAD: Ki=4.5uM
    PDBbind: -logKd/Ki=5.35, Ki=4.5uM
    17 4yx9:B (1.75) BS01 4HY ? GO:0016787 ... A0A0M3KL26 26136396 MOAD: Ki=4.5uM
    PDBbind: -logKd/Ki=5.35, Ki=4.5uM
    18 4yx9:C (1.75) BS01 4HY ? GO:0016787 ... A0A0M3KL26 26136396 MOAD: Ki=4.5uM
    19 4yx9:D (1.75) BS01 4HY ? GO:0016787 ... A0A0M3KL26 26136396 MOAD: Ki=4.5uM
    Reference:
    • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
    • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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