Structure of PDB 6vlz Chain AQ Binding Site BS01

Receptor Information
>6vlz Chain AQ (length=86) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKHLKFIARTVMVQEGNVESAYRTLNRILTMDGLIEDIKHRRYYEKPCRR
RQRESYERCRRIYNMEMARKINFLMRKNRADPWQGC
Ligand information
>6vlz Chain AA (length=944) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
gaacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucacccccaauaaagcuaaaacucaccugaguuguaaaaaacucca
guugacacaaaauagacuacgaaaguggcuuuaacauaucugaacacaca
auagcuaagacccaaacugggauuagauaccccacuaugcuuagcccuaa
accucaacaguuaaaucaacaaaacugcucgccagaacacuacgagccac
agcuuaaaacucaaaggaccuggcggugcuucauaucccucuagaggagc
cuguucuguaaucgauaaaccccgaucaaccucaccaccucuugcucagc
cuauauaccgccaucuucagcaaacccugaugaaggcuacaaaguaagcg
caaguacccacguaaagacguuaggucaagguguagcccaugagguggca
agaaaugggcuacauuuucuaccccagaaacgauagcccuuaugaaacuu
aagggucgaagguggauuuagcaguaaacuaagaguagagugcuuaguug
aacagggcccugaagcgcguacacaccgcccgucacccuccucaaguaua
cuucaaaggacauuuaacuaaaaccccuacgcauuuauauagaggagaca
agucguaacaugguaaguguacuggaaagugcacuuggacgaac
..((((..<<<<<<.)))).<<<<<<.....<<<<<<<<..<.<<<.<<<
..<......>......<<........<<<....<<<.....>>>....>>
>...<<<<....<<<..<<<....>>>.>>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>>........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>.....>>>>>>....<<<((.....<<<<..
<<<<..........<<<<<<......<<<.<<<.<<<......>>>..>>
>.>>>............<<<....>>>>>>>>>.....>>>>...>>>>.
..<<<<<<<...<<...<<<<.........>>>>...>>>>>>>>..>..
.....<.<<<<<......))..>>>>>.>.>>>.<<.......<<<<...
.>>>>.....>>..>>>>>><<<<<.<<<<<<<...<<<.<<<<...<<<
<<<<<<<.....<<........>>..........<<<<<<<.......<<
.<<<..<<<<<<.......<<..<<<<<.....>>>.......>>..>>.
....<<<....>>>.........>>>...>>>>>>>>....>>>>>>>..
>>.>>>>>>>>.....<<<<.....>>>>.......<<<<<.........
>>>>>............>>>>.....<<<<<<<.........>>>>>>>.
....>>>...>>>>>>>>>>.>>.......<<.<...<<<<<<..<<<<<
..<..........<.......>..........>..>>>>>.>>>>>>...
.>.>>.........<<<<<<<<<....>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6vlz Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation.
Resolution2.97 Å
Binding residue
(original residue number in PDB)
A2 K3 D38 R42 K47 P48 C49 R52 Q53 Y57 R62 Y64 N65 A81 D82
Binding residue
(residue number reindexed from 1)
A1 K2 D37 R41 K46 P47 C48 R51 Q52 Y56 R61 Y63 N64 A80 D81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6vlz, PDBe:6vlz, PDBj:6vlz
PDBsum6vlz
PubMed32737313
UniProtP82921|RT21_HUMAN Small ribosomal subunit protein bS21m (Gene Name=MRPS21)

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