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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
ada1a_human S192A ada1a_human F193L ada1a_human Y194F
5ht2a_rat W200A 5ht2a_rat W336A 5ht2a_rat F365L
5ht2a_rat W367A 5ht2a_rat Y370A 5ht6r_rat T196A
5ht6r_rat A154S ada2a_human S165A drd3_human Y36L
ada1b_mesau S135A casr_human L773R casr_human F806S
5ht1b_human S181A 5ht1b_human F185A 5ht1b_human F185M
5ht1b_human S334A 5ht1b_human F354A 5ht1b_human F354Y
adrb2_human C116F gipr_rat T340P 5ht2a_rat S239A
5ht2a_rat S207A sctr_human R299 sctr_human I353
sctr_human A375 mc4r_human V67 mc4r_human F267
mc4r_human F202 mc3r_rat F197 grm4_rat A595
grm4_rat A600 grm4_rat A601 grm4_rat A631
grm4_rat A638 grm4_rat A668 grm4_rat A669
grm4_rat A701 grm4_rat A771 grm4_rat A800
grm4_rat A830 grm4_rat C636 grm4_rat C715
grm4_rat C755 grm4_rat C767 grm4_rat C795
grm4_rat Q710 grm4_rat G598 grm4_rat G632
grm4_rat G660 grm4_rat G662 grm4_rat G713
grm4_rat G758 grm4_rat G788 grm4_rat G835
grm4_rat I599 grm4_rat I633 grm4_rat I644
grm4_rat I657 grm4_rat I665 grm4_rat I702
grm4_rat I705 grm4_rat I707 grm4_rat I714
grm4_rat I754 grm4_rat I772 grm4_rat I787
grm4_rat I796 grm4_rat I802 grm4_rat I804
grm4_rat L590 grm4_rat L592 grm4_rat L594
grm4_rat L603 grm4_rat L625 grm4_rat L629
grm4_rat L630 grm4_rat L635 grm4_rat L642
grm4_rat L659 grm4_rat L661 grm4_rat L670
grm4_rat L671 grm4_rat L700 grm4_rat L706
grm4_rat L709 grm4_rat L711 grm4_rat L712
grm4_rat L751 grm4_rat L753 grm4_rat L756


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