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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
c5ar_human P257 c5ar_human Y300 fpr1_human L156
fpr1_human P256 ada1a_human I85A ada1a_human I276
drd3_human F45 adrb2_mesau Y174 pacr_rat V318
vipr1_rat V277 vipr1_rat I298 vipr1_rat H355
vipr1_rat Q382 adrb1_human G177 ada2a_mouse Y216
ada2a_mouse C117 cckar_rat Y386A ssr2_human A263
ssr2_human A303 ssr2_human R256 ssr2_human N276
ssr2_human C225 ssr2_human C227 ssr2_human C268
ssr2_human G216 ssr2_human I209 ssr2_human I210
ssr2_human I214 ssr2_human I223 ssr2_human I224
ssr2_human I260 ssr2_human I266 ssr2_human I274
ssr2_human L215 ssr2_human L218 ssr2_human L221
ssr2_human L226 ssr2_human L229 ssr2_human L270
ssr2_human L300 ssr2_human M257 ssr2_human F208
ssr2_human F213 ssr2_human F217 ssr2_human F265
ssr2_human F267 ssr2_human F272 ssr2_human F275
ssr2_human F296 ssr2_human P271 ssr2_human S259
ssr2_human T212 ssr2_human T222 ssr2_human T255
ssr2_human T301 ssr2_human W269 ssr2_human Y211
ssr2_human Y228 ssr2_human Y273 ssr2_human Y302
ssr2_human V219 ssr2_human V254 ssr2_human V258
ssr2_human V261 ssr2_human V262 ssr2_human V264
ssr2_human V297 ssr2_human V298 ssr2_human V299
acm3_rat A110 acm3_rat A112 acm3_rat A150
acm3_rat A153 acm3_rat A184 acm3_rat A191
acm3_rat A200 acm3_rat A202 acm3_rat A235
acm3_rat A237 acm3_rat A238 acm3_rat N122
acm3_rat N152 acm3_rat N157 acm3_rat D113
acm3_rat D147 acm3_rat C111 acm3_rat G117
acm3_rat G185 acm3_rat G189 acm3_rat G233
acm3_rat I115 acm3_rat I116 acm3_rat I119


Reference:

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