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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
acm1_mouse I383 acm1_mouse L367 acm1_mouse L371
acm1_mouse L372 acm1_mouse L376 acm1_mouse L386
acm1_mouse M384 acm1_mouse F374 acm1_mouse P380
acm1_mouse S368 acm1_mouse T377 acm1_mouse T379
acm1_mouse W378 acm1_mouse Y381 acm1_mouse V385
acm1_mouse V387 cxcr1_human Y46 cxcr2_human Y55
oprd_mouse S135 oprd_mouse V188 oprm_rat S154
oprm_rat T207 ntr1_human I258 drd2_human Y209
ada2a_human E107 ada2a_human I211 adrb2_human A119
adrb2_human A128 adrb2_human A202 adrb2_human A46
adrb2_human A57 adrb2_human A76 adrb2_human A78
adrb2_human A85 adrb2_human A91 adrb2_human A92
adrb2_human R151 adrb2_human N51 adrb2_human D113
adrb2_human D79 adrb2_human C116 adrb2_human C125
adrb2_human C77 adrb2_human E107 adrb2_human E122
adrb2_human G162 adrb2_human G37 adrb2_human G50
adrb2_human G83 adrb2_human G90 adrb2_human I112
adrb2_human I121 adrb2_human I127 adrb2_human I153
adrb2_human I154 adrb2_human I159 adrb2_human I169
adrb2_human I201 adrb2_human I205 adrb2_human I214
adrb2_human I38 adrb2_human I43 adrb2_human I47
adrb2_human I55 adrb2_human I58 adrb2_human L115
adrb2_human L124 adrb2_human L155 adrb2_human L163
adrb2_human L167 adrb2_human L212 adrb2_human L42
adrb2_human L45 adrb2_human L53 adrb2_human L75
adrb2_human L80 adrb2_human L84 adrb2_human M156
adrb2_human M215 adrb2_human M36 adrb2_human M40
adrb2_human M82 adrb2_human F108 adrb2_human F166
adrb2_human F208 adrb2_human F217 adrb2_human F49
adrb2_human F89 adrb2_human P168 adrb2_human P211
adrb2_human P88 adrb2_human S111 adrb2_human S120


Reference:

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