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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
glr_rat V369 glr_rat V397 glr_rat V399
nk1r_rat Y305A nk1r_rat Y305F tshr_human I661
tshr_human S505N tshr_human V597L tshr_human L629F
tshr_human D633H tshr_human I630L tshr_human D633A
glp1r_rat F324 glp1r_rat V323 glp1r_rat L322
glp1r_rat F321 glp1r_rat R326 glp1r_rat I325
glp1r_rat I328 glp1r_rat V327 glp1r_rat C329
glp1r_rat F321A glp1r_rat L322A glp1r_rat F324A
glp1r_rat V327A glp1r_rat I328A glp1r_rat C329A
glp1r_rat L268A agtra_rat L122 agtra_rat A145
agtra_rat L143 agtra_rat K146 agtra_rat T148
agtra_rat V144 agtra_rat V147 agtra_rat I241
ghrhr_human A143 ghrhr_human A147 ghrhr_human A248
ghrhr_human A373 ghrhr_human N296 ghrhr_human N302
ghrhr_human N346 ghrhr_human N380 ghrhr_human C377
ghrhr_human Q368 ghrhr_human G136 ghrhr_human G249
ghrhr_human G251 ghrhr_human G258 ghrhr_human G287
ghrhr_human G294 ghrhr_human G298 ghrhr_human G339
ghrhr_human G363 ghrhr_human G365 ghrhr_human G369
ghrhr_human H137 ghrhr_human H341 ghrhr_human I139
ghrhr_human I141 ghrhr_human I148 ghrhr_human I150
ghrhr_human I284 ghrhr_human I285 ghrhr_human I289
ghrhr_human I303 ghrhr_human I335 ghrhr_human I340
ghrhr_human I343 ghrhr_human I344 ghrhr_human I371
ghrhr_human I374 ghrhr_human L144 ghrhr_human L151
ghrhr_human L245 ghrhr_human L247 ghrhr_human L252
ghrhr_human L255 ghrhr_human L291 ghrhr_human L299
ghrhr_human L301 ghrhr_human L332 ghrhr_human L334
ghrhr_human L337 ghrhr_human L348 ghrhr_human L362
ghrhr_human L364 ghrhr_human L375 ghrhr_human L379
ghrhr_human K286 ghrhr_human F145 ghrhr_human F242


Reference:

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