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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
agtrb_rat S109I agtrb_rat T33I agtrb_rat I37T
agtrb_rat I43V agtrb_rat L68M agtrb_rat L78V
agtrb_rat V108A agtrb_rat S109A agtrb_rat V147L
agtrb_rat I150V agtrb_rat M155V agtrb_rat I245V
agtrb_rat V254I agtrb_rat S252A agtrb_rat A283G
agtrb_rat N295S agtrb_rat N295A agtrl_xenla A108S
agtrl_xenla C251S agtrl_xenla I109V agtrl_xenla T110S
agtrl_xenla L247F agtrl_xenla S74A agtrl_xenla T115A
agtrl_xenla T116S agtrl_xenla S294N drd2_human S194C
drd2_human I195C drd2_human V196C drd2_human S197C
drd2_human F198C drd2_human Y199C drd2_human V200C
drd2_human P201C drd2_human F202C drd2_human I203C
drd2_human V204C drd2_human T205C drd2_human L206C
drd2_human L207C drd2_human V208C drd2_human Y209C
drd2_human I210C ada1a_rat S188A ada1a_rat S192A
ada1b_mesau N63D hrh2_canfa G187S acm5_human Y213F
acm5_human C214W acm5_human L212V acm5_human C214G
acm5_human Y213S acm5_human C214S acm5_human C214R
acm5_human L212F acm5_human Y213D acm5_human C214Y
acm5_human Y213H acm5_human L212I acm5_human Y213N
acm5_human C214F acm5_human Y213C lshr_human M398T
c5ar_human M120L ednrb_human L347K oprd_human W284A
oprd_human W284K oprd_human A275G oprd_human F280A
oprd_human V283A oprd_human A299G oprd_human L302A
oprd_human A309G nk1r_human F268H opsd_bovin A153C
opsd_bovin I154C opsd_bovin M155C ssr2_mouse F296L
ssr2_mouse V297S ednrb_human K182M ednrb_human K182R
ednrb_human K182A ednrb_human K182D ednrb_human K182E
ednrb_human K182X opsd_human K296E opsd_astfa Y261F
gnrhr_human K121R gnrhr_human K121D 5ht2a_rat F240L
galr1_human H112Q galr1_human H264A galr1_human H267A


Reference:

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