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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
adrb2_mesau S204A adrb2_mesau S207A adrb2_mesau Y219L
adrb2_mesau Y316A drd1_human S198A drd1_human S199A
drd2_mouse H394L drd2_mouse D80A drd2_mouse D80E
drd2_mouse S194A drd2_mouse S197A acm3_human A495
acm3_human A499 acm3_human A545 acm3_human N508
acm3_human N536 acm3_human N540 acm3_human C533
acm3_human C543 acm3_human C547 acm3_human G529
acm3_human I496 acm3_human I501 acm3_human I502
acm3_human I509 acm3_human I535 acm3_human L493
acm3_human L497 acm3_human L498 acm3_human L512
acm3_human L528 acm3_human L532 acm3_human L546
acm3_human M510 acm3_human F500 acm3_human P506
acm3_human P541 acm3_human S494 acm3_human S537
acm3_human T503 acm3_human T505 acm3_human T538
acm3_human W504 acm3_human W531 acm3_human Y507
acm3_human Y530 acm3_human Y534 acm3_human Y544
acm3_human V511 acm3_human V513 acm3_human V539
acm3_human V542 acm3_rat S120A acm3_rat N507D
hrh1_human D107N hrh1_human D107E hrh1_cavpo T203A
hrh1_cavpo N207A opsd_human G51V opsd_human P53R
opsd_human L125R opsd_human C167R opsd_human P171L
opsd_human H211P opsd_human H211R opsd_human P267L
opsd_bovin F45L opsd_bovin G51R opsd_bovin G51V
opsd_bovin P53R opsd_bovin V87D opsd_bovin G89D
opsd_bovin C167R opsd_bovin P170L opsd_bovin P171L
opsd_bovin H211P opsd_bovin C222R opsd_bovin K296D
opsd_bovin H211C opsd_bovin F115A opsd_bovin W126F
opsd_bovin W161L opsd_bovin H211R opsd_bovin P267G
opsd_bovin P267S opsd_bovin P267N opsd_bovin Y274F
nk1r_human T40A nk1r_human Q284A nk1r_human E78A
nk1r_human E78Q nk1r_human N85Q nk1r_human N85S


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