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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
gasr_human V105L gasr_human L143F gasr_human S144N
gasr_human A172L gasr_human R173K gasr_human G183F
gasr_human L184T gasr_human L185I gasr_human V187T
gasr_human I229L gasr_human F228L gasr_human A235V
gasr_human V232L gasr_human L336I gasr_human Y350F
gasr_human V349I gasr_human L388I gasr_human V389I
gasr_human M73T gasr_human T59L gasr_human V63L
gasr_human A149S gasr_human L133F gasr_human V136T
gasr_human L180C gasr_human V176A gasr_human A235M
gasr_human I229T gasr_human L225I gasr_human L347M
gasr_human A383S gasr_human A381T gasr_human H376L
5ht1a_human D82N 5ht1a_human D116N 5ht1a_human S199A
5ht1a_human T200A 5ht1a_human D82A 5ht1a_human S391A
5ht1a_human S393A 5ht1a_human N396V 5ht1a_human N396Q
5ht1a_human N396A 5ht1a_human N396F 5ht1a_human N386V
5ht1a_rat N396Y 5ht1b_human T355N 5ht2a_human S242A
5ht2a_rat D120N 5ht2a_rat D155N 5ht2a_rat M132L
5ht2a_rat F125S 5ht2a_rat F125L 5ht2a_rat F339L
5ht2a_rat F340L 5ht2a_rat A242S 5ht2a_rat A242T
5ht2a_rat A242V ada2a_human D113N ada2a_human D79N
ada2a_human S200A ada2a_human S204A ada2a_human F412N
ada2a_mouse S201C adrb2_human C77S adrb2_human C285S
adrb2_human D79N adrb2_human T164I adrb2_human N312F
adrb2_human N312A adrb2_human N312T adrb2_human N312Q
adrb2_human Y326A adrb2_mesau C77V adrb2_mesau C116V
adrb2_mesau C285V adrb2_mesau F289A adrb2_mesau F290M
adrb2_mesau N318K adrb2_mesau S319A adrb2_mesau Y326L
adrb2_mesau D79A adrb2_mesau D113N adrb2_mesau P323S
adrb2_mesau D113E adrb2_mesau D113S adrb2_mesau S120A
adrb2_mesau S161A adrb2_mesau S165A adrb2_mesau S203A
adrb2_mesau S204A adrb2_mesau S207A adrb2_mesau Y219L


Reference:

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