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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
opsg_human A285T opsg_human F277Y opsg_human F309Y
opsg_human L275F opsg_human F279V opsg_human S233A
opsg_human T230I opsg_human V236M opsg_human V274I
opsg_human I65T opsr_human S180A opsr_human Y277F
opsr_human T285A opsr_human T65I opsr_human I230T
opsr_human A233S opsr_human Y309F agtra_rat H256A
agtra_rat H256R agtra_rat H256Q agtra_rat H256E
tshr_human T441A ada2a_pig D79N ada2a_pig Y426A
ada2a_pig F429A ada1a_rat M292L ada1a_rat V185A
ada1b_mesau F96S ada1b_mesau S95T ada1b_mesau L182F
ada1b_mesau S208A ada1b_mesau L314M ada1b_mesau T174L
ada1b_mesau A313V acm2_human I389L acm2_human L390S
acm5_human S445L c5ar_human C293S c5ar_human C294S
c5ar_human C86S c5ar_human P90A c5ar_human N119Q
c5ar_human C157S c5ar_human P170A c5ar_human C221S
c5ar_human P214A c5ar_human P257A c5ar_human C285S
c5ar_human P297A ssr1_human M141Q ssr1_human V139I
ssr1_human S308V ssr1_human L307F ssr1_human M285L
ssr1_human F195Y ssr1_human V193M ssr1_human V289I
nk2r_human H267F nk2r_human F293A nk2r_human F270A
nk2r_human F89A nk2r_human N86A nk2r_human N90A
nk2r_human D79A nk2r_human Q109A nk2r_human F112A
nk2r_human T115A nk2r_human Q166V nk2r_human H198A
nk2r_human Y206A nk2r_human Y266A nk2r_human Y266F
nk2r_human Y266S nk2r_human H267L nk2r_human S170A
nk2r_human Y169A 5ht2a_human N376D 5ht2a_human D120N
5ht2a_human D120A 5ht2a_human N376A agtra_rat N295D
gasr_human A62S gasr_human V63I gasr_human I75V
gasr_human V77T gasr_human G70L gasr_human M67L
gasr_human A104C gasr_human A106F gasr_human L102M
gasr_human V105L gasr_human L143F gasr_human S144N


Reference:

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