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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
hrh1_cavpo F435A hrh1_cavpo F436A hrh1_human D107
hrh1_human D107A hrh1_human S155A hrh1_human T194
hrh1_human T194A hrh1_human N198 hrh1_human N198A
hrh2_canfa D186A hrh2_canfa T190A mshr_sheep D121N
mc3r_human V81I mc3r_human I183N mc4r_human V50M
mc4r_human F51L mc4r_human S58C mc4r_human E61A
mc4r_human N62S mc4r_human D90A mc4r_human G98R
mc4r_human E100A mc4r_human I102S mc4r_human I102T
mc4r_human I103V mc4r_human V103I mc4r_human I125F
mc4r_human D126A mc4r_human D126L mc4r_human D126N
mc4r_human D126S mc4r_human S127L mc4r_human I129A
mc4r_human C130A mc4r_human I137T mc4r_human I170V
mc4r_human F184L mc4r_human F184M mc4r_human F184S
mc4r_human C196A mc4r_human T199A mc4r_human M200A
mc4r_human M200V mc4r_human F202L mc4r_human T203A
mc4r_human M204A mc4r_human H214A mc4r_human L250Q
mc4r_human I251L mc4r_human G252S mc4r_human V253I
mc4r_human W258A mc4r_human F261A mc4r_human F262A
mc4r_human H264A mc4r_human F267A mc4r_human F267L
mc4r_human H283A mc4r_human F284A mc4r_human N285A
mc4r_human S295P mc4r_human D298A mc4r_human P299H
mc4r_human I301T mc4r_mouse V103I mc4r_mouse W174C
mc4r_mouse A175T mc4r_pig D298N mc4r_rat F267L
mtr1a_human M107D mtr1a_human M107T mtr1a_human A157V
mtr1a_human V192A mtr1a_human V192T mtr1a_human H195A
mtr1a_human P253A mtr1a_human A279S mtr1a_human S280A
mtr1a_human S280F mtr1a_human A284G mtr1a_sheep V208A
mtr1a_sheep V208L mtr1a_sheep H211F mtr1a_sheep H211L
mtr1b_human S123A mtr1b_human S127A mtr1b_human S127N
mtr1b_human N175A mtr1b_human N175H mtr1b_human V205A
mtr1b_human H208A mtr1b_human H208F mtr1b_human F209A


Reference:

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