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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
drd2_human L207 drd2_human L40 drd2_human L41
drd2_human L43 drd2_human L44 drd2_human L54
drd2_human L72 drd2_human L76 drd2_human L81
drd2_human L82 drd2_human L86 drd2_human L94
drd2_human M116 drd2_human M155 drd2_human M57
drd2_human M88 drd2_human F110 drd2_human F164
drd2_human F172 drd2_human F198 drd2_human F50
drd2_human P169 drd2_human P201 drd2_human P89
drd2_human S121 drd2_human S129 drd2_human S157
drd2_human S163 drd2_human S167 drd2_human S194
drd2_human S197 drd2_human S75 drd2_human T112
drd2_human T119 drd2_human T153 drd2_human T165
drd2_human T205 drd2_human T39 drd2_human T42
drd2_human T85 drd2_human W160 drd2_human W90
drd2_human Y199 drd2_human Y93 drd2_human V111
drd2_human V115 drd2_human V152 drd2_human V154
drd2_human V159 drd2_human V161 drd2_human V196
drd2_human V200 drd2_human V204 drd2_human V208
drd2_human V47 drd2_human V49 drd2_human V53
drd2_human V55 drd2_human V59 drd2_human V74
drd2_human V78 drd2_human V83 drd2_human V87
drd2_human V91 drd2_human V92 oprx_rat L98T
oprx_rat L99T oprx_rat A125S oprx_rat T122I
oprx_rat Q277H oprx_rat V276I oprx_rat V278I
oprx_rat T302I oprx_rat A213K oprx_rat L56S
fshr_rat D407N fshr_rat Y548F ada1b_mesau C128C
ada1b_mesau F310S ada1b_mesau F311S ada1b_mesau F310E
opsd_bovin D83I opsd_bovin E122G opsd_bovin E122E
opsd_bovin M86I opsd_bovin D83G ada2a_human C201C
ada2a_human I202S ada2a_human G203S ada2a_human S204S
adrb2_human N312C adrb2_human H296A adrb2_human D113A


Reference:

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