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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
ccr5_human V150 ccr5_cerae V150 c3ar_human Y160
ssr1_mouse L106 ssr1_mouse L114 ssr1_mouse L107F
5ht1b_human I333K 5ht1b_human S334E 5ht1d_human I195
5ht1d_human S196 5ht1d_human C203 5ht1d_human S210
5ht1d_human I199 5ht1d_human I215 5ht1d_human S196L
5ht1d_human I199V 5ht1d_human C203V 5ht1d_human I208F
5ht1a_rat G348 5ht1b_rat G313 gnrhr_human A312
gnrhr_human N315 gnrhr_human D319 gnrhr_human C317
gnrhr_human G287 gnrhr_human G324 gnrhr_human I288
gnrhr_human I322 gnrhr_human L286 gnrhr_human L310
gnrhr_human L314 gnrhr_human L321 gnrhr_human F292
gnrhr_human F307 gnrhr_human F308 gnrhr_human F309
gnrhr_human F311 gnrhr_human F313 gnrhr_human F318
gnrhr_human F326 gnrhr_human P282 gnrhr_human P316
gnrhr_human P320 gnrhr_human W289 gnrhr_human W291
gnrhr_human Y283 gnrhr_human Y284 gnrhr_human Y290
gnrhr_human Y323 gnrhr_human Y325 gnrhr_human V285
drd2_human F382 drd2_human A120 drd2_human A127
drd2_human A38 drd2_human A46 drd2_human A58
drd2_human A77 drd2_human A79 drd2_human A84
drd2_human N124 drd2_human N52 drd2_human D114
drd2_human D80 drd2_human C118 drd2_human C126
drd2_human C168 drd2_human C56 drd2_human G173
drd2_human G51 drd2_human I109 drd2_human I122
drd2_human I128 drd2_human I130 drd2_human I156
drd2_human I158 drd2_human I166 drd2_human I195
drd2_human I203 drd2_human I45 drd2_human I48
drd2_human I73 drd2_human L113 drd2_human L123
drd2_human L125 drd2_human L162 drd2_human L170
drd2_human L171 drd2_human L174 drd2_human L206
drd2_human L207 drd2_human L40 drd2_human L41


Reference:

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