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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
adrb3_human G53F adrb3_human D117L adrb3_human N312A
v2r_human A125 v2r_human A132 v2r_human A163
v2r_human A165 v2r_human A210 v2r_human A216
v2r_human A42 v2r_human A50 v2r_human A52
v2r_human A60 v2r_human A61 v2r_human A63
v2r_human A84 v2r_human A87 v2r_human A89
v2r_human A98 v2r_human N55 v2r_human D85
v2r_human C82 v2r_human Q119 v2r_human Q174
v2r_human Q92 v2r_human Q96 v2r_human G122
v2r_human G220 v2r_human G56 v2r_human G79
v2r_human H80 v2r_human I130 v2r_human I177
v2r_human I209 v2r_human I46 v2r_human I78
v2r_human L118 v2r_human L131 v2r_human L135
v2r_human L161 v2r_human L168 v2r_human L169
v2r_human L170 v2r_human L172 v2r_human L175
v2r_human L211 v2r_human L219 v2r_human L41
v2r_human L43 v2r_human L44 v2r_human L53
v2r_human L57 v2r_human L59 v2r_human L62
v2r_human L81 v2r_human L83 v2r_human L86
v2r_human L90 v2r_human L94 v2r_human L97
v2r_human M120 v2r_human M123 v2r_human M129
v2r_human M133 v2r_human M212 v2r_human F166
v2r_human F176 v2r_human F178 v2r_human F214
v2r_human F48 v2r_human F91 v2r_human P173
v2r_human P217 v2r_human P95 v2r_human S126
v2r_human S127 v2r_human S167 v2r_human S171
v2r_human S45 v2r_human S54 v2r_human T134
v2r_human T207 v2r_human T218 v2r_human W164
v2r_human W208 v2r_human Y124 v2r_human Y128
v2r_human V121 v2r_human V160 v2r_human V162
v2r_human V206 v2r_human V213 v2r_human V215


Reference:

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