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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
adrb2_human P88 adrb2_human S111 adrb2_human S120
adrb2_human S161 adrb2_human S165 adrb2_human S203
adrb2_human S204 adrb2_human S207 adrb2_human S220
adrb2_human S41 adrb2_human S74 adrb2_human T110
adrb2_human T118 adrb2_human T123 adrb2_human T164
adrb2_human T56 adrb2_human T73 adrb2_human W109
adrb2_human W158 adrb2_human Y209 adrb2_human V114
adrb2_human V117 adrb2_human V126 adrb2_human V129
adrb2_human V152 adrb2_human V157 adrb2_human V160
adrb2_human V206 adrb2_human V210 adrb2_human V213
adrb2_human V216 adrb2_human V218 adrb2_human V39
adrb2_human V44 adrb2_human V48 adrb2_human V52
adrb2_human V54 adrb2_human V81 adrb2_human V86
adrb2_human V87 5ht2a_rat Y254 5ht2c_rat A58
aa1r_bovin M201 oprk_mouse L79 oprk_mouse A64
oprk_mouse N77 oprk_mouse G73 oprk_mouse G76
oprk_mouse I62 oprk_mouse L74 oprk_mouse F70
oprk_mouse S67 oprk_mouse S78 oprk_mouse T63
oprk_mouse Y66 oprk_mouse V65 oprk_mouse V68
oprk_mouse V69 oprk_mouse V71 oprk_mouse V72
oprk_mouse V75 oprd_mouse L69 oprd_mouse A49
oprd_mouse A51 oprd_mouse A54 oprd_mouse A58
oprd_mouse A61 oprd_mouse N67 oprd_mouse C60
oprd_mouse G63 oprd_mouse G66 oprd_mouse I50
oprd_mouse I52 oprd_mouse L48 oprd_mouse L55
oprd_mouse L64 oprd_mouse L65 oprd_mouse S57
oprd_mouse T53 oprd_mouse Y56 oprd_mouse V59
oprd_mouse V62 oprd_mouse V68 c5ar_human T168
ssr2_human P220 ssr2_human L91 c5ar_human L256S
c5ar_human G54 c5ar_human A81 c5ar_human L167
c5ar_human P257 c5ar_human Y300 fpr1_human L156


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