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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
ada2a_pig F383 ada2a_pig F388 ada2a_pig F390
ada2a_pig F391 ada2a_pig F392 ada2a_pig F410
ada2a_pig F411 ada2a_pig F412 ada2a_pig F414
ada2a_pig F429 ada2a_pig P389 ada2a_pig P423
ada2a_pig S419 ada2a_pig S420 ada2a_pig T393
ada2a_pig T395 ada2a_pig T427 ada2a_pig W387
ada2a_pig W413 ada2a_pig Y394 ada2a_pig Y416
ada2a_pig Y426 ada2a_pig V375 ada2a_pig V378
ada2a_pig V379 ada2a_pig V382 ada2a_pig V384
ada2a_pig V385 ada2a_pig V424 ada2a_pig D113N
ccr5_mouse H90 cxcr4_rat N116 cxcr4_human N119
adrb1_rat S232 adrb1_rat F350 adrb1_rat F351
adrb3_rat S209 ada1a_human L186 ada1a_human L190
ada1a_human V185A oprk_rat S324 oprk_rat Y313
oprk_rat Y312 adrb1_human I97 adrb2_human I72
adrb2_human V307A adrb2_human Y308A adrb2_human I309A
adrb2_human L310A adrb2_human L311A adrb2_human I314A
adrb2_human V317A adrb2_human G320A adrb2_human L324A
crfr1_human W234 crfr1_human F269 crfr1_human M305
oprx_human M134 oprk_human M142 oprd_human M132
oprm_human M153 oprk_mouse M142 oprm_rat M151
cxcr4_felca N120 v1ar_rat C237 v1ar_rat C349
acm2_human Y206 gasr_rat A147 gasr_rat L180
cckar_rat A149 aa1r_human A237 aa1r_human A244
aa1r_human A273 aa1r_human A282 aa1r_human A289
aa1r_human N254 aa1r_human N280 aa1r_human N284
aa1r_human C255 aa1r_human G279 aa1r_human H251
aa1r_human H278 aa1r_human I199 aa1r_human I239
aa1r_human I252 aa1r_human I256 aa1r_human I268
aa1r_human I272 aa1r_human I274 aa1r_human I286
aa1r_human L190 aa1r_human L193 aa1r_human L194


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