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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
oprk_mouse P289 oprk_mouse P327 oprk_mouse S323
oprk_mouse S324 oprk_mouse T247 oprk_mouse T288
oprk_mouse T321 oprk_mouse W287 oprk_mouse Y246
oprk_mouse Y312 oprk_mouse Y313 oprk_mouse Y320
oprk_mouse Y330 oprk_mouse V232 oprk_mouse V236
oprk_mouse V239 oprk_mouse V244 oprk_mouse V276
oprk_mouse V278 oprk_mouse V279 oprk_mouse V280
oprk_mouse V282 oprk_mouse V296 oprk_mouse V328
oprd_mouse A221 oprd_mouse A269 oprd_mouse A275
oprd_mouse A299 oprd_mouse A305 oprd_mouse A309
oprd_mouse N310 oprd_mouse C216 oprd_mouse C232
oprd_mouse C273 oprd_mouse C303 oprd_mouse G234
oprd_mouse G268 oprd_mouse G307 oprd_mouse H278
oprd_mouse H301 oprd_mouse I226 oprd_mouse I228
oprd_mouse I229 oprd_mouse I277 oprd_mouse I279
oprd_mouse I282 oprd_mouse I304 oprd_mouse L219
oprd_mouse L227 oprd_mouse L235 oprd_mouse L300
oprd_mouse L302 oprd_mouse L306 oprd_mouse F218
oprd_mouse F220 oprd_mouse F222 oprd_mouse F270
oprd_mouse F280 oprd_mouse P225 oprd_mouse P276
oprd_mouse T230 oprd_mouse W274 oprd_mouse W284
oprd_mouse Y233 oprd_mouse Y308 oprd_mouse V217
oprd_mouse V223 oprd_mouse V224 oprd_mouse V231
oprd_mouse V265 oprd_mouse V266 oprd_mouse V267
oprd_mouse V271 oprd_mouse V272 oprd_mouse V281
oprd_mouse V283 crfr1_human Y124 crfr1_xenla F124
ada2a_pig A377 ada2a_pig N418 ada2a_pig N422
ada2a_pig C386 ada2a_pig C417 ada2a_pig G381
ada2a_pig G415 ada2a_pig I380 ada2a_pig I425
ada2a_pig I428 ada2a_pig L376 ada2a_pig L421
ada2a_pig F383 ada2a_pig F388 ada2a_pig F390


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