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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
nk1r_rat S122 nk1r_rat T124 nk1r_rat T217
nk1r_rat T86 nk1r_rat W155 nk1r_rat Y121
nk1r_rat Y167 nk1r_rat Y168 nk1r_rat Y205
nk1r_rat Y214 nk1r_rat Y216 nk1r_rat V126
nk1r_rat V149 nk1r_rat V150 nk1r_rat V153
nk1r_rat V156 nk1r_rat V211 nk1r_rat V218
nk1r_rat V219 nk1r_rat V72 nk1r_rat A36
nk1r_rat A37 nk1r_rat A38 nk1r_rat N50
nk1r_rat G49 nk1r_rat I42 nk1r_rat I54
nk1r_rat S46 nk1r_rat T40 nk1r_rat T45
nk1r_rat W35 nk1r_rat Y39 nk1r_rat V41
nk1r_rat V43 nk1r_rat V44 nk1r_rat V47
nk1r_rat V48 nk1r_rat V51 nk1r_rat V52
nk1r_rat V53 ccr5_human H88D ccr1_human I261
drd3_human L39 drd3_human Y88 drd3_human D75
drd3_human A123 drd3_human A151 drd3_human C166
drd3_human F188 drd3_human V381 ccr3_human L163
ccr3_macmu L163 mshr_human C253 mc3r_human C291
oprk_mouse A234 oprk_mouse A281 oprk_mouse A317
oprk_mouse A331 oprk_mouse N322 oprk_mouse N326
oprk_mouse C245 oprk_mouse C286 oprk_mouse C315
oprk_mouse G319 oprk_mouse H291 oprk_mouse I237
oprk_mouse I241 oprk_mouse I242 oprk_mouse I243
oprk_mouse I284 oprk_mouse I285 oprk_mouse I290
oprk_mouse I292 oprk_mouse I294 oprk_mouse I316
oprk_mouse L240 oprk_mouse L277 oprk_mouse L295
oprk_mouse L318 oprk_mouse L325 oprk_mouse L329
oprk_mouse L333 oprk_mouse F231 oprk_mouse F233
oprk_mouse F235 oprk_mouse F283 oprk_mouse F293
oprk_mouse F314 oprk_mouse F332 oprk_mouse P238
oprk_mouse P289 oprk_mouse P327 oprk_mouse S323


Reference:

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