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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

Other GPCR-related resources
GPCR resources from other laboratories
  • GPCRDB: information system for GPCRss
  • TinyGPAP mutant database
  • GPCR-OKB: oligomerization knowledge base
  • GPCR natural variants database
  • GLIDA: GPCR-ligand database
  • IUPHAR GPCR database
  • gpDB: G proteins and their interactions with GPCRs
  • SEVENS: GPCR genes database
  • GDD: GPCR decoy database
  • Summary of activation changes in GPCR TMs


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11002 entries in GPCR-RD.
GPCR-RD Home

GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
nk1r_rat H265 nk1r_rat I251 nk1r_rat I259
nk1r_rat I303 nk1r_rat I304 nk1r_rat L262
nk1r_rat L288 nk1r_rat L293 nk1r_rat M249
nk1r_rat M250 nk1r_rat M291 nk1r_rat M295
nk1r_rat M299 nk1r_rat F257 nk1r_rat F264
nk1r_rat F267 nk1r_rat F268 nk1r_rat P263
nk1r_rat P302 nk1r_rat S290 nk1r_rat S296
nk1r_rat S297 nk1r_rat T256 nk1r_rat T298
nk1r_rat W261 nk1r_rat W292 nk1r_rat Y287
nk1r_rat Y300 nk1r_rat Y305 nk1r_rat V252
nk1r_rat V253 nk1r_rat V254 nk1r_rat V266
nk1r_rat V286 nk1r_rat A114 nk1r_rat A115
nk1r_rat A118 nk1r_rat A125 nk1r_rat A127
nk1r_rat A158 nk1r_rat A162 nk1r_rat A215
nk1r_rat A75 nk1r_rat A77 nk1r_rat A79
nk1r_rat A82 nk1r_rat A83 nk1r_rat N109
nk1r_rat N73 nk1r_rat N85 nk1r_rat C80
nk1r_rat Q165 nk1r_rat E78 nk1r_rat G166
nk1r_rat G213 nk1r_rat H108 nk1r_rat I113
nk1r_rat I120 nk1r_rat I151 nk1r_rat I154
nk1r_rat I204 nk1r_rat I212 nk1r_rat L116
nk1r_rat L157 nk1r_rat L159 nk1r_rat L160
nk1r_rat L161 nk1r_rat L203 nk1r_rat L207
nk1r_rat L209 nk1r_rat L210 nk1r_rat L71
nk1r_rat L74 nk1r_rat M123 nk1r_rat M81
nk1r_rat F107 nk1r_rat F110 nk1r_rat F111
nk1r_rat F117 nk1r_rat F128 nk1r_rat F152
nk1r_rat F163 nk1r_rat F206 nk1r_rat F70
nk1r_rat F76 nk1r_rat F84 nk1r_rat P112
nk1r_rat P164 nk1r_rat P208 nk1r_rat S119
nk1r_rat S122 nk1r_rat T124 nk1r_rat T217


Reference:

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