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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
lshr_rat P624F ednrb_human I138 ednrb_human I197
cnr1_human I119 cnr1_human F155 cnr1_human A233
cnr1_human Y275 cnr1_human Y365 cnr2_human A150
par1_human L333 aa3r_rat C267 aa3r_rat I129
aa3r_rat L234 ada1b_mesau A204 ada1b_mesau L314
ada1a_rat V185 ada1a_rat M292 5ht1b_human T221
acm5_human I78 acm5_human A163 acm5_human A446
acm5_human C498 acm2_human I71 drd3_human A209
drd2_human I210 adrb2_human Y219 ada1a_human G34
ada1a_human F39 ada1a_human L42 ada1a_human L29
ada1a_human I32 ada1a_human I85 ada1a_human T76
ada1a_human N100 ada1a_human M115 ada1a_human A152
ada1a_human L148 ada1a_human F163 ada1a_human I159
ada1a_human I157 ada1a_human V185 ada1a_human A189
ada1a_human L197 ada1a_human I199 ada1a_human L201
ada1a_human L286 ada1a_human L290 ada1a_human I294
ada1a_human I310 ada1a_human L317 ada1a_human I321
ada1a_rat I200 ccr1_human I216 ccr2_human G224
acm2_rat A401 acm2_human L70 acm2_human A156
acm5_human L77 acm1_pig L367 acm1_pig T202
acm2_pig I201 acm2_pig I389 glr_rat A183
glr_rat A189 glr_rat A238 glr_rat A315
glr_rat A367 glr_rat A398 glr_rat R309
glr_rat R325 glr_rat N180 glr_rat N239
glr_rat N319 glr_rat N405 glr_rat D386
glr_rat C241 glr_rat C270 glr_rat C402
glr_rat Q393 glr_rat E246 glr_rat E363
glr_rat G179 glr_rat G190 glr_rat G235
glr_rat G247 glr_rat G272 glr_rat G274
glr_rat G360 glr_rat G394 glr_rat H178
glr_rat H362 glr_rat I177 glr_rat I236


Reference:

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