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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

Other GPCR-related resources
GPCR resources from other laboratories
  • GPCRDB: information system for GPCRss
  • TinyGPAP mutant database
  • GPCR-OKB: oligomerization knowledge base
  • GPCR natural variants database
  • GLIDA: GPCR-ligand database
  • IUPHAR GPCR database
  • gpDB: G proteins and their interactions with GPCRs
  • SEVENS: GPCR genes database
  • GDD: GPCR decoy database
  • Summary of activation changes in GPCR TMs


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11002 entries in GPCR-RD.
GPCR-RD Home

GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
lshr_human F588 lshr_human F594 lshr_human F611
lshr_human F621 lshr_human F626 lshr_human P584
lshr_human P613 lshr_human P620 lshr_human S586
lshr_human S591 lshr_human S616 lshr_human T577
lshr_human T580 lshr_human Y612 lshr_human Y623
lshr_human V609 drd1_human I205A drd1_human I205Y
drd1_human L286A drd1_human L286Y oprd_human W284L
oprd_human H301N aa2ar_human T88A aa2ar_human T88S
aa2ar_human T88R aa2ar_human Q89A aa2ar_human S90A
aa2ar_human S91A aa2ar_human S277C aa2ar_human S281N
aa2ar_human Q89N aa2ar_human Q89S aa2ar_human Q89L
aa2ar_human Q89H aa2ar_human Q89R v2r_human L44P
v2r_human L44F v2r_human W164S v2r_human S167L
v2r_human S167T v2r_human S167A oprk_rat T109A
oprk_rat D105N oprx_human Q280H adrb2_human N312
adrb2_human N318 adrb2_human N322 adrb2_human G315
adrb2_human G320 adrb2_human I309 adrb2_human I314
adrb2_human I325 adrb2_human L310 adrb2_human L311
adrb2_human L324 adrb2_human F321 adrb2_human P323
adrb2_human S319 adrb2_human W313 adrb2_human Y308
adrb2_human Y316 adrb2_human Y326 adrb2_human V307
adrb2_human V317 adrb2_human N293 adrb2_human C285
adrb2_human G276 adrb2_human G280 adrb2_human H296
adrb2_human I277 adrb2_human I278 adrb2_human I291
adrb2_human I294 adrb2_human L275 adrb2_human L284
adrb2_human L287 adrb2_human M279 adrb2_human F282
adrb2_human F289 adrb2_human F290 adrb2_human P288
adrb2_human T281 adrb2_human T283 adrb2_human W286
adrb2_human V292 adrb2_human V295 adrb2_human V297
adrb2_mesau A320 adrb2_mesau N293 adrb2_mesau N312
adrb2_mesau N318 adrb2_mesau N322 adrb2_mesau C285


Reference:

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