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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
oprm_rat I77 oprm_rat L74 oprm_rat L83
oprm_rat L88 oprm_rat M72 oprm_rat F84
oprm_rat F87 oprm_rat S76 oprm_rat Y75
oprm_rat V78 oprm_rat V80 oprm_rat V81
oprm_rat V89 oprd_mouse S177L oprm_rat S196L
oprm_mouse D147A trfr_mouse T102Y trfr_mouse Q105E
trfr_mouse Q105L trfr_rat C100S trfr_rat C100A
v2r_human V278 v2r_human V279 v2r_human Y280C
v2r_human L292F v2r_human A285 v2r_human A314
v2r_human A326 v2r_human N317 v2r_human N321
v2r_human C283 v2r_human C319 v2r_human Q291
v2r_human I276 v2r_human I324 v2r_human L274
v2r_human L282 v2r_human L289 v2r_human L292
v2r_human L309 v2r_human L310 v2r_human L312
v2r_human L313 v2r_human L316 v2r_human M311
v2r_human F287 v2r_human F288 v2r_human F328
v2r_human P286 v2r_human P322 v2r_human S315
v2r_human S318 v2r_human S327 v2r_human T320
v2r_human W284 v2r_human W293 v2r_human W323
v2r_human Y280 v2r_human Y325 v2r_human V275
v2r_human V277 v2r_human V281 v2r_human V290
opsd_human F45L opsd_human T58R opsd_human V87D
opsd_human G89D ptafr_human D63N ssr1_mouse S305F
fshr_human D581G fshr_human D581Y fshr_human C584R
drd2_human L407C drd2_human Y408C drd2_human S409C
drd2_human A410C drd2_human F411C drd2_human W413C
drd2_human L414C drd2_human G415C drd2_human Y416C
drd2_human V417C drd2_human N418C drd2_human S419C
drd2_human A420C drd2_human V421C drd2_human N422C
drd2_human P423C drd2_human I424C drd2_human I425C
drd2_human Y426C drd2_human T427C drd2_human T428C


Reference:

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