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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
fshr_rat T549S fshr_rat T575 fshr_rat T575M
fshr_rat D580G fshr_rat Y614 fshr_rat Y614H
lshr_pig A373V lshr_pig M398T lshr_pig L457R
lshr_pig I542L lshr_pig C543R lshr_pig A572V
lshr_pig I575L lshr_pig T577I lshr_pig D578E
lshr_pig D578G lshr_pig D578H lshr_pig D578Y
lshr_pig C581R lshr_pig A593P lshr_pig S616Y
lshr_pig I625K lshr_rat D409 lshr_rat D409N
lshr_rat D409S lshr_rat A445T lshr_rat T450A
lshr_rat E455D lshr_rat E455Q lshr_rat E455S
lshr_rat S457A lshr_rat L461R lshr_rat P505A
lshr_rat P505G lshr_rat P505L lshr_rat N539G
lshr_rat Y550F lshr_rat D582A lshr_rat D582G
lshr_rat D582H lshr_rat D582N lshr_rat D582Q
lshr_rat D582Y lshr_rat M586L lshr_rat P588L
lshr_rat P588Y lshr_rat S590A lshr_rat A593G
lshr_rat K609A lshr_rat K609D lshr_rat K609E
lshr_rat K609L lshr_rat K609P lshr_rat K609Q
lshr_rat K609R lshr_rat L612A lshr_rat V613A
lshr_rat Y616A lshr_rat P617L lshr_rat P617Y
lshr_rat N619A lshr_rat N619D lshr_rat N619K
lshr_rat N619Q lshr_rat N619R lshr_rat S620A
lshr_rat C621A lshr_rat C621M lshr_rat N623A
lshr_rat N623D lshr_rat N623K lshr_rat N623Q
lshr_rat N623R lshr_rat P624L lshr_rat Y627A
lshr_rat Y627P lshr_rat F630A lshr_rat F630Y
tshr_mouse P556L tshr_rat D474 tshr_rat C636
hrh1_cavpo W161A hrh1_cavpo W161F hrh1_cavpo W161M
hrh1_cavpo W167A hrh1_cavpo W167F hrh1_cavpo W167M
hrh1_cavpo W174A hrh1_cavpo F433A hrh1_cavpo F433M
hrh1_cavpo F435A hrh1_cavpo F436A hrh1_human D107


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