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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
drd2_human C118K drd2_human C118S drd2_human V154I
drd2_human M155P drd2_human S167A drd2_human F172C
drd2_human S194A drd2_human S197A drd2_human I377C
drd2_human V378C drd2_human L379C drd2_human G380C
drd2_human V381C drd2_human F382C drd2_human I383C
drd2_human I384C drd2_human W386C drd2_human L387C
drd2_human P388C drd2_human F389C drd2_human F390A
drd2_human F390C drd2_human I391C drd2_human T392C
drd2_human H393C drd2_human I394C drd2_human L395C
drd2_human N396C drd2_human I397C drd2_human Y408V
drd2_human T412C drd2_rat N52A drd2_rat N52L
drd2_rat N52Q drd2_rat D80A drd2_rat S121A
drd2_rat S121L drd2_rat S121N drd2_rat N124A
drd2_rat N124L drd2_rat N124Q drd2_rat S194
drd2_rat S194A drd2_rat S197 drd2_rat S197A
drd2_rat H394 drd2_rat S420A drd2_rat S420L
drd2_rat S420N drd2_rat S420V drd3_human C114S
drd3_human S192 drd3_human S193 drd3_human S196
drd4_human L90W drd4_human F91V drd4_human S94L
drd4_human L111F drd4_human M112V drd4_rat F88V
ednrb_horse I118K ednrb_mouse W276C ednrb_mouse P285L
ednrb_rat A144T ednrb_rat K182D ednrb_rat C283Y
ednrb_rat F332A ednrb_rat C335A ednrb_rat W336A
ednrb_rat P338A ednrb_rat S342K ednrb_rat K346A
ednrb_rat D368A ednrb_rat N373A ednrb_rat M374K
ednrb_rat N378P ednrb_rat S379K ednrb_rat I381A
ednrb_rat P383K ednrb_rat I384A ednrb_rat A385K
ednrb_rat L386A ednrb_rat V389K fshr_pig L460R
fshr_rat L491 fshr_rat T494 fshr_rat T549
fshr_rat T549A fshr_rat T549D fshr_rat T549I
fshr_rat T549S fshr_rat T575 fshr_rat T575M


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