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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
grpr_mouse R309D grpr_mouse F313A brs3_human R127Q
brs3_human S315A bkrb2_rat D108N bkrb2_rat Y147F
bkrb2_rat W187F bkrb2_rat N234A bkrb2_rat F284A
bkrb2_rat W288F bkrb2_rat F291A bkrb2_rat F291V
bkrb2_rat Q292A bkrb2_rat T295A bkrb2_rat Q320A
bkrb2_rat Y327A cnr2_human D80E cnr2_human D80N
cnr2_human K109A cnr2_human K109R cnr2_human W158A
cnr2_human W158F cnr2_human W158Y cnr2_human S161A
cnr2_human V164I cnr2_human S165A cnr2_human S193G
cnr2_human Y299A fpr1_human D71A fpr1_human D106A
fpr1_human D106N fpr1_human R163F fpr1_human R205A
fpr1_human S244A cxcr4_human I53L cxcr4_human D84N
cxcr4_human H113A cxcr4_human D171N cxcr4_human F199G
cxcr4_human Q200A cxcr4_human F201A cxcr4_human F201G
cxcr4_human F201L cxcr4_human H203A cxcr4_human D262
cxcr4_human D262A cxcr4_human D262N cxcr4_human E288Q
cxcr4_human H294A gasr_canfa L355V gasr_rat I58A
gasr_rat D100N gasr_rat V187T gasr_rat F227A
gasr_rat F347A gasr_rat W351A gasr_rat H381F
gasr_rat H381L gasr_rat H381R gasr_rat N391A
gasr_rat N391D drd1_human I49 drd1_human D70
drd2_bovin I378C drd2_human A77C drd2_human V78C
drd2_human A79C drd2_human D80C drd2_human L81C
drd2_human L82C drd2_human V83C drd2_human A84C
drd2_human T85C drd2_human L86C drd2_human V87C
drd2_human M88C drd2_human P89C drd2_human W90C
drd2_human W90L drd2_human V91C drd2_human V91F
drd2_human V92C drd2_human Y93C drd2_human L94C
drd2_human L94S drd2_human F110L drd2_human V111M
drd2_human D114C drd2_human D114N drd2_human D114S
drd2_human C118K drd2_human C118S drd2_human V154I


Reference:

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